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. noneImmunoglobulin therapy, also known as normal human immunoglobulin ( NHIG), is the use of a mixture of (immunoglobulins) to treat a number of health conditions.
These conditions include, certain cases of and, and in certain other infections when a more specific immunoglobulin is not available. Depending on the formulation it can be given by, a,. The effects last a few weeks.Common side effects include pain at the site of injection, muscle pain,. Other severe side effects include,.
Use is not recommended in people with some types of. Use appears to be relatively safe during. Human immunoglobulin is made from human. It contains antibodies against many.Human immunoglobulin therapy first occurred in the 1930s and a formulation for injection into a vein was approved for medical use in the United States in 1981. It is on the, the safest and most effective medicines needed in a. Each formulation of product is somewhat different.
In the United Kingdom a dose cost the between 11.20 and 1,200.00 pounds depending on the type and amount. A number of specific immunoglobulin formulations are also available including for,. Contents.Medical use Immunoglobulin therapy is used in a variety of conditions, many of which involve decreased or abolished antibody production capabilities, which range from a complete absence of multiple types of antibodies, to (usually involving IgG2 or IgG3 ), to other disorders in which antibodies are within a normal quantitative range, but lacking in quality - unable to respond to antigens as they normally should – resulting in an increased rate or increased severity of infections. In these situations, immunoglobulin infusions confer passive resistance to infection on their recipients by increasing the quantity/quality of IgG they possess.
Immunoglobulin therapy is also used for a number of other conditions, including in many autoimmune disorders such as in an attempt to decrease the severity of symptoms. Immunoglobulin therapy is also used in some treatment protocols for such as (HIV), some autoimmune disorders (such as and ), some neurological diseases (, and ) some acute infections and some complications of organ transplantation.Immunoglobulin therapy is especially useful in some acute infection cases such as infection and is also considered the standard of treatment for some autoimmune disorders such as.
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